A double manhunt is now under way to find the attackers, both described as Asian men in their early 20s.
Police said the first attack happened this week in an isolated part of Birmingham’s Witton railway station, between 7pm on Tuesday and 2am on Wednesday.
The girl had walked to the station with her friend before being led away by a man who then raped her.
She left the station shortly after the attack and flagged down a passing vehicle to ask for help.
She was then raped again after getting into the second man’s car.
Detectives from British Transport Police and West Midlands Police have launched a major investigation to try to identify both attackers and appeal for witnesses.
The first attacker is described as having light skin, brown eyes, a skinny build and is about 6ft tall.
He was wearing a tracksuit and black trainers.
The second attacker is described as being around 5ft 7in, of large build with a close-cropped beard, wearing a blue jumper and black jeans.
Detective Chief Inspector Tony Fitzpatrick said: “My detectives are currently examining all available CCTV in an effort to identify the offenders and whilst these enquiries are made, we are keen to speak with any potential witnesses.
“Your information could prove vital in our enquiries to identify the perpetrators.”
:: Anyone with information is asked to get in touch by sending a text to 61016 or by calling 0800 405040 quoting reference 65 of 26/07/2017.
Alternatively, people can contact Crimestoppers anonymously on 0800 555111.